The Art of Process Chemistry

Providing must-have knowledge for the pharmaceutical industry and process chemists in industry, this ready reference offers solutions for saving time and money and supplying — in a sustainable way — valuable products. Application-oriented and well structured, each chapter presents successful strategies for the latest modern drugs, showing how to provide very fast bulk quantities of drug candidates. Throughout, the text illustrates how all the key factors are interwoven and dependent on one another in creating optimized methods for optimal products.

Preface
 
Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate
 
CCR5 Receptor Antagonist
 
5a-Reductase Inhibitors - The Finasteride Story
 
Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist
 
SERM: Selective Estrogen Receptor Modulator
 
HIV Integrase Inhibitor: Raltegravir
 
Cyclopentane-Based NK1 Receptor Antagonist
 
Glucokinase Activator
 
CB1R Inverse Agonist - Taranabant

• Edited by Nobuyoshi Yasuda