NMR in Organometallic Chemistry

The first and ultimate guide for anyone working in transition organometallic chemistry and related fields, providing the background and

practical guidance on how to efficiently work with routine research problems in NMR.

The book adopts a problem-solving approach with many examples taken from recent literature to show readers how to interpret the data.

Perfect for PhD students, postdocs and other newcomers in organometallic and inorganic chemistry, as well as for organic chemists

involved in transition metal catalysis.

PREFACE
 
INTRODUCTION
 
ROUTINE MEASURING AND RELAXATION
Getting Started
Relaxation
 
COSY AND HMQC 2-D SEQUENCES
Tactics
COSY
HMQC and HMBC
 
OVERHAUSER EFFECTS AND 2-D NOESY
Background
Assigning Signals via NOEs and General Applications
X,1H Overhauser Effects
2-D NOESY
HOESY
Metal Complexes and NOEs. ROESY vs NOESY
 
DIFFUSION CONSTANTS VIA NMR MEASUREMENTS
 
CHEMICAL SHIFTS
1HNMR
Introduction to Heavy Atom NMR
13C
15N NMR
19F NMR
31P NMR
Transition Metals
 
COUPLING CONSTANTS
Background
One-Bond Interactions
A Short 19F Excursion
Applications Involving 1J
1J(H,D) and Molecular Hydrogen Complexes
1J(C,H) in ¿2-C-H M Complexes: Agostic Interactions
Remote Agostic Bonds
1J(Si,H) in ¿2-Si-H M Complexes
Trans Influence and 1J
Two- and Three-Bond J-Values
 
DYNAMICS
Variable Temperature
Line Shape Analysis
Magnetization Transfer
Two-Dimensional NMR and Chemical Exchange
 
PREFACE TO THE PROBLEMS
 
ORGANOMETALLIC INTRODUCTION
Oxidative Addition
Migratory Insertion (or Intramolecular Nucleophilic Attack)
External Nucleophilic Attack
Beta-Hydrogen Elimination
Reductive Elimination
Synthesis of Transition Metal?Hydride Complexes
Synthesis of Transition Metal Alkyl Complexes
Synthesis of Transition Metal Carbonyl Complexes
Synthesis of Transition Metal Olefin Complexes
Synthesis of Transition Metal Carbene Complexes
 
NMR PROBLEMS
Three Sample Problems
NMR Problems
 
SOLUTIONS TO THE PROBLEMS AND COMMENTS

• By (author) Paul S. Pregosin

"Ein super-Buch für die experimentell arbeitenden Studierenden, beginnend mit dem Bachelorstudium bis hin zur Promotionsphase."
Prof. Dr. Rüdiger Beckhaus, Universität Oldenburg
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