Amide Bond Activation

Provides a thorough overview of the pivotal role of the amide bond in organic synthesis – an indispensable source of information for researchers in academia and industry!

1) Bridged Lactams as Model Systems for Amidic Distortion
2) Modification of Amidic Resonance Through Heteroatom Substitution at Nitrogen - Anomeric Amides
3) Amide Bond Activation by Twisting and Nitrogen Pyramidalization
4) Transition-Metal-Free Reactions of Amides by Tetrahedral Intermediates
5) Electrophilic Amide Bond Functionalisation
6) Transamidation of Carboxamides and Amide Derivatives: Mechanistic Insights, Concepts, and Reactions
7) Amide Bond Esterification and Hydrolysis
8) Activation of Amide C-N Bonds by Nickel Catalysis
9) Pd-NHC Catalysis in Cross-Coupling of Amides
10) Cross-Coupling of Amides through Decarbonylation
11) Transition Metal-Catalyzed Radical Reactions of Amides
12) Weinreb Amide as a Multifaceted Directing Group in C-H Activation
13) Computational Studies of Amide C-N Bond Activation
14) Esters as Viable Acyl Cross-Coupling Electro-Philes
15) Cross-Coupling of Aromatic Esters by Decarbonylation

• Edited by Michal Szostak