Process Analytical Technology for Pharmaceutical Freeze-Drying

Edited by Geoff Smith Edited by Davide Fissore

Book cover: Process Analytical Technology for Pharmaceutical Freeze-Drying

Extent: 496 pages

Publisher: Wiley-VCH

Subjects: Technical Sciences: Computer Science, Engineering, IT, & Math

Language: English

Hardback (Forthcoming)

(September 2026)

ISBN: 9783527354658

6.69 x 9.65 inches

Price: $212.00

On back order

Provides insights into an essential pharmaceutical process technology and shows the reader how proper monitoring can enable their process development and guarantee product quality.


Provides insights into an essential pharmaceutical process technology and shows the reader how proper monitoring can enable their process development and guarantee product quality.

1. Freeze-drying of parenteral drug products - An Introduction
2. Standard PAT instrumentation: Temperature sensors
3. Standard PAT instrumentation: Pressure gauges and vapour pressure sensors
4. Wireless sensor networks for lyophilization
5. Monitoring methods based on the measure of the sublimation flow: Pressure Rise Test and other direct technologies
6. Spectroscopic-based PAT in freeze-drying
7. An introduction to Through-Vial Impedance Spectroscopy (TVIS)
8. An application for Through-Vial Impedance Spectroscopy (TVIS) in modelling of the ice sublimation process
9. Freeze-drying monitoring and control using thermal imaging
10. Multiplexing PAT for qualitative ice sublimation monitoring in primary drying
11. Emerging technologies in pharmaceutical freeze-drying
12. Innovations in control of freezing in pharmaceutical processes

  • Edited by Geoff Smith
  • Edited by Davide Fissore