Directed Selectivity in Organic Synthesis

Bringing together examples that until now were often hidden and widely spread throughout the original literature, this textbook shows how to use the correct reagents, conditions or reaction sequences to have access to all possible stereoisomers when beginning synthesis with only a single starting material.

 

Adopting a didactic approach, the authors have chosen general and simple examples throughout the book so that these reactions can be transferred easily to other reaction types.

 

While of major interest to master and PhD students alike, this book is also a source of valuable information for organic chemists in both academia and industry.

 

Additional material for lectures at www.wiley-vch.de/textbooks

Preface
 
GENERAL METHODS TO DIRECT SELECTIVITY
Chemoselectivity
Regioselectivity
Stereoselectivity
Enantioselectivity
 
DIRECT SELECTIVITY: ACETYLENES AND ALKENES
Acetylenes
Alkenes
 
DIRECT SELECTIVITY WITH CARBONYL DERIVATIVES
Carbonyl Compounds as Electrophiles
Conjugate Addition to Carbonyl Compounds
 
DIRECTED SELECTIVITY WITH CARBONYL DERIVATIVES
Carbonyl Compounds as Electrophiles
Conjugate Addition to Carbonyl Compounds
Enolate Derivatives
Miscellaneous
 
SELECTIVITY AT SP3 - CENTERS AND HETEROATOMS
Epoxides
Acetals
Ethers
Alcohols and Phenols
Sulfur Compounds
Amines
Halogen Compounds
 
Index

• By (author) Tanja Gaich
• By (author) Ekkehard Winterfeldt