Pharmaceutical Nanotechnology

With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book.

Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!

Foreword
Industrial Requirements on Nanopharmacy Research
Introduction
 
Volume 1
 
PART I. ENTRY TO THE NANOPHARMACY REVOLUTION
History: Potential, Challenges, and Future Development in Nanopharmaceutical Research and Industry
Nanoscale Drugs: A Key to Revolutionary Progress in Pharmacy and Healthcare
The Emergence of Nanopharmacy: From Biology to Nanotechnology and Drug Molecules to Nanodrugs
Understanding and Characterizing Functional Properties of Nanoparticles
Omics-Based Nanopharmacy: Powerful Tools Towards Precision Medicine
 
PART II. FUNDAMENTALS OF NANOTECHNOLOGY IN PHARMACY
Nanostructure in Drug Delivery
Characterization Methods: Physical and Chemical Characterization Techniques
Nanoparticle Characterization Methods: Applications of Synchrotron and Neutral Radiation
Overview of Techniques and Description of Established Processes
Nanopharmacy: Exploratory Methods for Polymeric Materials
Overview and Presentation of Exploratory Methods for Manufacturing Nanoparticles / "Inorganic Materials"
Scale-Up and cGMP Manufacturing of Nanodrug Delivery Systems for Clinical Investigations
Occupational Safety and Health
 
Volume 2
 
PART III. DEVELOPMENT OF NANOPHARMACEUTICALS
 
Micro- and Nano-Tools in Drug Discovery
Computational Predictive Models for Nanomedicine
Drug Targeting in Nanomedicine and Nanopharmacy: A Systems Approach
Nanoparticle Toxicity: General Overview and Insights Into Immunological Compatibility
An Overview of Nanoparticle Biocompatibility for Their Use in Nanomedicine
Translation to the Clinic: Preclinical and Clinical Pharmacology Studies of Nanoparticles - The Translational Challenge
Regulatory Issues in Nanomedicines
Social Studies of Nanopharmaceutical Research
 
PART IV. PHARMACEUTICAL APPLICATIONS OF NANOMATERIALS
Nanoparticles for Imaging and Imaging Nanoparticles: State of the Art and Current Prospects
Nanoparticle-Based Physical Methods for Medical Treatments
Nanodrugs in Medicine and Healthcare: Oral Delivery
Steroidal Nanodrugs Based on Pegylated Nanoliposomes Remote Loaded with Amphipathic Weak Acids Steroid Prodrugs as Anti-Inflammatory Agents
Nanodrugs in Medicine and Healthcare: Pulmonary, Nasal and Ophthalmic Routes, and Vaccination
Neurodegenerative Diseases - Alzheimer's Disease
 
PART V. THE NANOPHARMACEUTICAL MARKET
A Practical Guide to Translating Nanomedical Products
Development and Commercialization of Nanocarrier-Based Drug Products
Future Outlook of Nanopharmacy: Challenges and Opportunities
 
Index

• Edited by Jean Cornier
• Edited by Andrew Owen
• Edited by Arno Kwade
• Edited by Marcel Van de Voorde
• Series edited by Marcel Van de Voorde