Industrial Biotechnology

The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production.

Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.

Of interest to biotechnologists and microbiologists, as well as those working in the biotechnological, chemical, food and pharmaceutical industries.

PART I - INDUSTRIAL BIOTECHNOLOGY: FROM PIONEERS TO VISIONARY
1. History of Industrial Biotechnology
2. Synthetic Biology: An Emerging Approach for Strain Engineering
3. Towards Efficient Genome-Scale Metabolic Pathway Analysis
4. Cell-Free Synthetic Systems for Metabolic Engineering and Biosynthetic Pathway Prototyping
 
PART II - MULTI-PURPOSE BACTERIAL CELL FACTORIES
5. Industrial Biotechnology: Escherichia coli as a Host
6. Industrial Microorganisms: Corynebacterium glutamicum
7. Host Organisms: Bacillus subtilis
8. Host Organisms: P. putida
 
PART III - EXPLOITING ANAEROBIC BIOSYNTHETIC POWER
9. Host Organisms: Clostridium acetobutylicum/ Clostridium beijerinckii and Related Organisms
10. Advances in Consolidated Bioprocessing Using Clostridium thermocellum and Thermoanaerobacter saccharolyticum
11. Lactic Acid Bacteria
 
PART IV - MICROBIAL TREASURE CHESTS FOR HIGH-VALUE NATURAL COMPOUNDS
12. Host Organisms: Myxobacterium
13. Host Organisms: Streptomyces
 
PART V - EXTENDING THE RAW MATERIAL BASIS FOR BIO-PRODUCTION
14. Extreme Thermophiles as Metabolic Engineering Platforms: Strategies and Current Perspective
15. Cyanobacteria as a Host Organism
16. Host Organisms: Algae
 
PART VI - EUKARYOTIC WORKHORSES: COMPLEX CELLS ENABLE COMPLEX PRODUCTS
17. Host Organisms: Mammalian Cells
18. Host Organisms: Saccharomyces cerevisiae
19. Industrial Microorganisms: Pichia pastoris

• Edited by Christoph Wittmann
• Edited by James C. Liao
• Series edited by Sang Yup Lee
• Series edited by Jens Nielsen
• Series edited by Gregory Stephanopoulos